Okekunle, Akinkunmi Paul and Jones, Stephanie and Adeniji, Olaleye and Watkins, Caroline Leigh and Hackett, Maree and Di Tanna, Gian Luca (2023) Stroke in Africa: A systematic review and meta-analysis of the incidence and case-fatality rates. [DataSet]

Description

Background:
The burden of stroke (a leading cause of disability and mortality) in Africa appears to be increasing, but a systematic review of the best available data to support or refute this observation is lacking.

Aim:
To determine the incidence and 1-month case-fatality rates from high-quality studies of stroke epidemiology among Africans.

Summary of review:
We searched and retrieved eligible articles on stroke epidemiology among indigenous Africans in bibliographic databases (MEDLINE, ScienceDirect, Google Scholar, and Cochrane library) using predefined search terms from the earliest records through January 2022. Methodological assessment of eligible studies was conducted using the Newcastle–Ottawa scale. Pooling of incidence and case-fatality rates was performed via generalized linear models (Poisson-Normal random-effects model). Of the 922 articles retrieved, 14 studies were eligible for inclusion. The total number of stroke cases was 2568, with a population denominator (total sample size included in population-based registries or those who agreed to participate in door-to-door community studies) of 3,384,102. The pooled crude incidence rate of stroke per 100,000 persons in Africa was 106.49 (95% confidence interval (CI) = 58.59–193.55), I2 = 99.6%. The point estimate of the crude incidence rate was higher among males, 111.33 (95% CI = 56.31–220.12), I2 = 99.2%, than females, 91.14 (95% CI = 47.09–176.37), I2 = 98.9%. One-month case-fatality rate was 24.45 (95% CI = 16.84–35.50), I2 = 96.8%, with lower estimates among males, 22.68 (95% CI = 18.62–27.63), I2 = 12.9%, than females, 27.57 (95% CI = 21.47–35.40), I2 = 51.6%.

Conclusion:
The burden of stroke in Africa remains very high. However, little is known about the dynamics of stroke epidemiology among Africans due to the dearth of high-quality evidence. Further continent-wide rigorous epidemiological studies and surveillance programs using the World Health Organization STEPwise approach to Surveillance (WHO STEPS) framework are needed.

Research / Data Type:	Collection - various types
Depositing User:	CLoK admin
Date Deposited:	14 Feb 2023 10:52
Revision:	12
URI:	https://uclandata.uclan.ac.uk/id/eprint/364
Additional details Additional details Creators: Creators Email ORCID Okekunle, Akinkunmi Paul UNSPECIFIED UNSPECIFIED Jones, Stephanie SJones10@uclan.ac.uk UNSPECIFIED Adeniji, Olaleye UNSPECIFIED UNSPECIFIED Watkins, Caroline Leigh CLWatkins@uclan.ac.uk UNSPECIFIED Hackett, Maree MHackett1@uclan.ac.uk UNSPECIFIED Di Tanna, Gian Luca UNSPECIFIED UNSPECIFIED Schools: School of Nursing and Midwifery* > Community Health and Midwifery* Date: 2023 Contact email address: rdmsupport@uclan.ac.uk Last Modified: 24 Jul 2023 12:40

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Stroke in Afric ... -fatality rates Stroke in Afric ... -fatality rates Stroke in Afric ... -fatality rates Resource Title: Stroke in Africa: A systematic review and meta-analysis of the incidence and case-fatality rates Resource Type: This dataset stored elsewhere Resource Identifier: 10.25384/SAGE.c.6386225.v1 Identifier Type: DOI URL: https://doi.org/10.25384/SAGE.c.6386225.v1

Stroke in Afric ... -fatality rates Stroke in Afric ... -fatality rates Stroke in Afric ... -fatality rates Resource Title: Stroke in Africa: A systematic review and meta-analysis of the incidence and case-fatality rates Resource Type: Publication Resource Identifier: 10.1177/17474930221147164 Identifier Type: DOI URL: https://doi.org/10.1177/17474930221147164 CLoK URL: https://clok.uclan.ac.uk/44961/