Gupta, Swarnim and Lowe, Nicola and Moran, Victoria and Sinclair, Jonathan and Zaman, Mukhtiar and Fatima, Sadia and Shahzad, Babar Biofortification with Zinc and Iron for Eliminating Deficiency in Pakistan (BiZIFED2). [DataSet]

Description

The data set pertains to BiZIFED2 randomised controlled trial (RCT) which was a household-based, double-blind, cluster-randomized controlled trial conducted in rural Pakistan. The primary focus of the BiZiFED2 RCT was to evaluate the impact of zinc-biofortified wheat flour consumption on biomarkers of zinc status, growth, and zinc-related morbidity in adolescent girls aged 10-16 year. As biofortified wheat was provided to the entire household in this study, children aged 1-5 years were included as a secondary population to assess potential spill over effects on their growth and morbidity. The study included 517 adolescence girls and 517 children from 486 households. The entire dataset consists of data for participating (1) Adolescent girls; (2) Children; (3) Household. The details of data are as follows :

Adolescent girls data includes: registration (general information) data for the participating adolescent girls collected at enrolment; haematological indices of micronutrient status for the participating adolescent girls collected at the beginning, middle and end of intervention phase; anthropometric measurement data for the participating adolescent girls collected at the beginning, middle and end of intervention phase; information on respiratory tract infection for the participating adolescent girls collected at every 2-week intervals; Pulmonary Function Test (Spirometry) data for participating adolescent girls conducted at the beginning, middle and end of intervention phase.

Data on children includes: registration (general information) data for the participating children aged collected at enrolment; anthropometric measurement data for the participating children collected at the beginning, middle and end of intervention phase; data on respiratory tract infection for the participating children collected at every 2-week intervals;
data on diarrhoeal morbidity for the participating children collected at every 2-week intervals

Household level data: This includes demographics of the household, living conditions (such as water source, kitchen, and toilet facilities etc), details related to wheat flour consumption and purchase practices etc at baseline

Research / Data Type:	Dataset
Keywords:	Zinc, biofortification, adolescent girls, children, growth, morbidity, wheat, Pakistan, effectiveness, zinc status, minerals
DOI:	10.17030/uclan.data.00000588
Research Centres:	Global Development
Research Institutes:	Planetary Resilience and Community Transformations (PACT)
Depositing User:	Swarnim Gupta
Date Deposited:	11 Apr 2025 14:43
Revision:	42
URI:	https://uclandata.uclan.ac.uk/id/eprint/588
Additional details Additional details Creators: Creators Email ORCID Gupta, Swarnim sgupta6@uclan.ac.uk 0000-0002-5846-4954 Lowe, Nicola nmlowe@uclan.ac.uk 0000-0002-6934-2768 Moran, Victoria vlmoran@uclan.ac.uk 0000-0003-3165-4448 Sinclair, Jonathan jksinclair@uclan.ac.uk 0000-0002-2231-3732 Zaman, Mukhtiar mukhtiar.zaman@rmi.edu.pk UNSPECIFIED Fatima, Sadia sadiafatima@kmu.edu.pk 0000-0002-1677-5535 Shahzad, Babar babar.kmu@gmail.com 0000-0003-3810-2574 Schools: School of Health, Social Work and Sport* > Allied Health and Sport* Research Groups: International Institute of Nutritional Sciences and Applied Food Safety Studies Collection period: From To 4 November 2019 17 March 2021 Data collection method: Refer to articles: Gupta, S.; Zaman, M.; Fatima, S.; Shahzad, B.; Brazier, A.K.M.; Moran, V.H.; Broadley, M.R.; Zia, M.H.; Bailey, E.H.; Wilson, L.; et al. The Impact of Consuming Zinc-Biofortified Wheat Flour on Haematological Indices of Zinc and Iron Status in Adolescent Girls in Rural Pakistan: A Cluster-Randomised, Double-Blind, Controlled Effectiveness Trial. Nutrients 2022, 14, 1657. https://doi.org/10.3390/nu14081657 Gupta S, Zaman M, Fatima S, et al. The Impact of Consuming Zinc-Biofortified Wheat Flour on Haematological Indices of Zinc and Iron Status in Adolescent Girls in Rural Pakistan: A Cluster-Randomised, Double-Blind, Controlled Effectiveness Trial. Nutrients. 2022;14(8):1657. Published 2022 Apr 15. doi:10.3390/nu14081657 Lowe NM, Zaman M, Moran VH, et al. Biofortification of wheat with zinc for eliminating deficiency in Pakistan: study protocol for a cluster-randomised, double-blind, controlled effectiveness study (BIZIFED2). BMJ Open. 2020;10(11):e039231. Published 2020 Nov 18. doi:10.1136/bmjopen-2020-039231 Statement on legal, ethical and access issues: Ethical approval for the research was approved by the University of Central Lancashire STEMH Ethics Committee (reference number: STEMH 1014, date: 30 August 2019) in the UK and Khyber Medical University Ethics Committee (reference number: DIR/KMU-EB/BZ/000628, date: 7 May 2019) in Pakistan. All data collected was anonymised and stored on secure servers, with data protection protocols followed when information was shared between participating institutions. Refer following articles for further details: 1. Lowe NM, Zaman M, Moran VH, et al. Biofortification of wheat with zinc for eliminating deficiency in Pakistan: study protocol for a cluster-randomised, double-blind, controlled effectiveness study (BIZIFED2). BMJ Open. 2020;10(11):e039231. Published 2020 Nov 18. doi:10.1136/bmjopen-2020-039231 2. Gupta S, Zaman M, Fatima S, et al. The Impact of Consuming Zinc-Biofortified Wheat Flour on Haematological Indices of Zinc and Iron Status in Adolescent Girls in Rural Pakistan: A Cluster-Randomised, Double-Blind, Controlled Effectiveness Trial. Nutrients. 2022;14(8):1657. Published 2022 Apr 15. doi:10.3390/nu14081657 Keywords: Zinc, biofortification, adolescent girls, children, growth, morbidity, wheat, Pakistan, effectiveness, zinc status, minerals Projects: Grant Number Funder Name Funder ID BB/S013989/1 Biotechnology and Biological Sciences Research Council http://dx.doi.org/10.13039/501100000268 Contact email address: rdmsupport@uclan.ac.uk Last Modified: 11 Apr 2025 14:44

Available Files

Data

BiZiFED2_Adoles ... 6y_datasets.zip BiZiFED2_Adoles ... 6y_datasets.zip BiZiFED2_Adoles ... 6y_datasets.zip Visible to: Anyone Document Type : Data File Description: Contains data on haematological indices, anthropometric measurements, registration/general information, respiratory tract infection and Pulmonary Function Test (PFT) for the participating adolescent girls aged 10-16 years Metadata Revision: 6 Mime-Type: application/zip Language: English License: Creative Commons: Attribution 4.0 File size: 1MB

BiZiFED2_childr ... 5y_datasets.zip BiZiFED2_childr ... 5y_datasets.zip BiZiFED2_childr ... 5y_datasets.zip Visible to: Anyone Document Type : Data File Description: Contains data on anthropometric measurements, registration/general information, respiratory tract infection, diarrhoeal morbidity for the participating children aged 1-5 years Metadata Revision: 6 Mime-Type: application/zip Language: English License: Creative Commons: Attribution 4.0 File size: 1MB

BiZiFED2_Househ ... cs_dataset.xlsx BiZiFED2_Househ ... cs_dataset.xlsx BiZiFED2_Househ ... cs_dataset.xlsx Visible to: Anyone Document Type : Data File Description: Data on demographics of the household, living conditions (such as water source, kitchen, and toilet facilities etc), details related to wheat flour consumption and purchase practices etc at baseline Metadata Revision: 5 Mime-Type: application/vnd.openxmlformats-officedocument.spreadsheetml.sheet Language: English License: Creative Commons: Attribution 4.0 File size: 117kB

Read me

BiZiFED2_Data%2 ... 20document.docx BiZiFED2_Data%2 ... 20document.docx BiZiFED2_Data%2 ... 20document.docx Visible to: Anyone Document Type : README file File Description: Contains overview of data set organisation Metadata Revision: 2 Mime-Type: application/vnd.openxmlformats-officedocument.wordprocessingml.document Language: English License: Creative Commons: Attribution 4.0 File size: 16kB

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